Hazard Functions

Hazards Help You Better Define Disease Progression

  • Hazards are a fundamental representation of health event risk (i.e., progression, death).
  • Hazard Functions represents changing Hazard Rates over time.
  • TreeAge Pro allows you to visualize Hazards and Survival to accurately model disease progression.
  • Hazards can be used in all time-driven model types.
    • –> Markov event probabilities
    • –> Partitioned Survival Curves
    • –> Discrete Time-to-Event Distributions
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Hazard Table Editor

  • Edit Hazard Rates over time in the and see the impact of changes to the resulting Survival Curve.
  • Match survival to Kaplan-Meier data and extend hazards and survival into the future.

Convert Survival Data to Hazards

  • Survival data for a critical health event is frequently available (progression, death, device failure, etc.).
    • But integrating survival data into different model types can be difficult.
  • Convert the survival data to a hazard table, which can then be used to model progression in PartSA, Markov and DES models.

Use Hazards to Define Disease Progression

Health Risks Change
Hazard tables can represent event risk that changes over time.

Hazards Provide Flexibility
Use hazards in multiple model types.
Vary hazards with sensitivity analysis to study uncertainty.

Export Model Survival to Validate Risk
Generate survival curves from your model and export to a survival table.
Convert the survival table to hazards to examine the risk of death over time in your model.

Markov Models
Convert hazards to event probabilities for each cycle through a simple formula.

Partitioned Survival Models
Survival curves can be defined by hazard functions as well as survival functions.

Discrete Event Models
HazardTable distributions generate time-to-event samples based on the varying risk.

Hazard Webinars

Webinar 1 – Hazard Concepts, Hazard Table Editor

Download webinar materials

Webinar 2 – Using Hazards in Models

Download webinar materials

Webinar 3 – Hazards and Sensitivity Analysis

Download webinar materials

Hazard Tutorials

Tutorial 1 – Understanding Survival Curves and Hazard Functions

Download tutorial materials

  • Convert Kaplan Meier data into hazards and visualizing risk changes over time.
  • Comparing survival curves including Goodness of Fit measures.
  • Impact of hazard functions on survival data is discussed.

Tutorial 2 – Extrapolating Survival Curves inc. Mortality data

Download tutorial materials (Coming soon)

  • Extrapolate Survival Curves and visualize how risk changes over time.
  • Incorporate Background Mortality using rates.
  • Compare Survival Curves or Hazard Functions with the Survival Plotter.

Tutorial 3 – Sensitivity Analysis and Survival Curves and Hazard Functions

Download tutorial materials

  • Do Sensitivity Analysis on Survival Curves to visualize the limits of uncertainty and the impacts on your models.
  • Compare Survival Curves and Hazard Functions with the Survival Plotter to look at limits of uncertainty.

Please email support@treeage.com to request access to a beta installer including the Hazard Editor and related functionality.